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Mouse Anti-DPF1 Antibody (1A9) (CBMAB-0302-YC)

Provided herein are mouse monoclonal antibodies against Human DPF1. The antibody clone 1A9 can be used for immunoassay techniques, such as ChIP, IP, WB and MA.
See all DPF1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A9
Antibody Isotype
IgG2a
Application
ChIP, IP, WB, MA

Basic Information

Immunogen
Recombinant peptide
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
DPF1
Introduction
DPF1 (double PHD fingers 1), also known as D4, zinc and double PHD fingers family 1, is a protein that in humans is encoded by the DPF1 gene.
Entrez Gene ID
8193
UniProt ID
Q92782
Alternative Names
BAF45b; NEUD4; neuro-d4
Function
May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
Biological Process
Apoptotic process Source: ProtInc
Negative regulation of transcription, DNA-templated Source: GO_Central
Nervous system development Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Cytoplasm; Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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