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Mouse Anti-DYNLL2 Monoclonal Antibody (1G7) (CBMAB-1098-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1G7
Antibody Isotype
IgG2b
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant protein DYNLL2 (NP_542408, aa 1-72) with GST tag.
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
Located in aa 1-72, partial

Target

Full Name
Dynein Light Chain LC8-Type 2
Introduction
Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. DYNLL2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. DYNLL2 may play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Entrez Gene ID
140735
UniProt ID
Q96FJ2
Alternative Names
Dlc2; DNCL1B; RSPH22
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).
Biological Process
Cilium assembly Source: GO_Central
Microtubule-based process Source: InterPro
Positive regulation of ATP-dependent microtubule motor activity, plus-end-directed Source: GO_Central
Cellular Location
Cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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