Mouse Anti-DYNLL2 Monoclonal Antibody (1G7) (CBMAB-1098-YC)

Name: Mouse Anti-DYNLL2 Monoclonal Antibody (1G7)
SKU: CBMAB-1098-YC
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1G7

Application

ELISA, WB

Immunogen

Partial recombinant protein DYNLL2 (NP_542408, aa 1-72) with GST tag.

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

Located in aa 1-72, partial

More Infomation

Target

Full Name

Dynein Light Chain LC8-Type 2

Introduction

Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. DYNLL2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. DYNLL2 may play a role in changing or maintaining the spatial distribution of cytoskeletal structures.

Entrez Gene ID

140735

UniProt ID

Q96FJ2

Alternative Names

Dlc2; DNCL1B; RSPH22

Research Area

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).

Biological Process

Cilium assembly Source: GO_Central
Microtubule-based process Source: InterPro
Positive regulation of ATP-dependent microtubule motor activity, plus-end-directed Source: GO_Central

Cellular Location

Cytoskeleton

Li, Y., Yuan, P., Fan, S., Zhai, B., Jin, W., Li, D., ... & Kang, X. (2022). Weighted gene co-expression network indicates that the DYNLL2 is an important regulator of chicken breast muscle development and is regulated by miR-148a-3p. BMC genomics, 23(1), 1-12.

Jiang, J., Liu, D., Xu, G., Liang, T., Yu, C., Liao, S., ... & Zhan, X. (2021). TRIM68, PIKFYVE, and DYNLL2: The possible novel autophagy-and immunity-associated gene biomarkers for osteosarcoma prognosis. Frontiers in Oncology, 1238.

Cao, L., Fetterer, R., Qu, G., Zhang, X., & Tuo, W. (2019). Neospora caninum cytoplasmic dynein LC8 light chain 2 (NcDYNLL2) is differentially produced by pathogenically distinct isolates and regulates the host immune response. Parasitology, 146(5), 588-595.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Alternative Versions

Mouse Anti-DYNLL2 Recombinant Antibody (1G7) (CAT#: V2LY-0425-LY1147)

Related Products

Mouse Anti-DYNLL2 Recombinant Antibody (CBYCD-115) (CAT#: V2LY-0425-LY1148)

Mouse Anti-DYNLL2 Recombinant Antibody (CBYCD-115) (CAT#: CBMAB-D2007-YC)

Mouse Anti-DYNLL2 Recombinant Antibody (1G7) (CAT#: V2LY-0425-LY1147)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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