DYNLL2
DYNLL2 (Dynein Light Chain LC8-Type 2) is a Protein Coding gene. Among its related pathways are COPI-independent Golgi-to-ER retrograde traffic and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include motor activity and cytoskeletal protein binding. An important paralog of this gene is DYNLL1.
Full Name
Dynein Light Chain LC8-Type 2
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).
Biological Process
Cilium assembly Source: GO_Central
Microtubule-based process Source: InterPro
Positive regulation of ATP-dependent microtubule motor activity, plus-end-directed Source: GO_Central
Microtubule-based process Source: InterPro
Positive regulation of ATP-dependent microtubule motor activity, plus-end-directed Source: GO_Central
Cellular Location
Cytoskeleton
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Anti-DYNLL2 antibodies
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Target: DYNLL2
Host: Mouse
Antibody Isotype: IgM
Specificity: Chicken
Clone: CBYCD-115
Application*: E, FN, IC, IF, P, WB
Target: DYNLL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1G7
Application*: E, WB
Target: DYNLL2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Rat, Cattle
Clone: CBYCD-115
Application*: F, IF, IP, WB
Target: DYNLL2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: 1G7
Application*: E, WB, IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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