Mouse Anti-DZIP3 Recombinant Antibody (3A1) (V2LY-0425-LY1169)

Name: Mouse Anti-DZIP3 Recombinant Antibody (3A1)
SKU: V2LY-0425-LY1169
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

3A1

Antibody Isotype

IgG2a, κ

Application

WB, ELISA

Basic Information

Immunogen

DZIP3 (aa1021-1120) partial recombinant protein.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

DAZ Interacting Zinc Finger Protein 3

Entrez Gene ID

9666

UniProt ID

Q86Y13

Research Area

E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.

Biological Process

Protein polyubiquitination Source: UniProtKB

Cellular Location

Cytoplasm

More Infomation

References

Kolapalli, S. P., Sahu, R., Chauhan, N. R., Jena, K. K., Mehto, S., Das, S. K., ... & Chauhan, S. (2021). RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer ProgressionDZIP3 Is a Novel Driver of Cell-Cycle and Cancer Progression. Cancer research, 81(2), 315-331.

Mamoor, S. (2021). DZIP3 is a differentially expressed gene in human metastatic breast cancer, in the brain and in the lymph nodes.

Quan, Y., Liang, F., Wu, D., Yao, X., Hu, Z., Zhu, Y., ... & Xiong, J. (2020). Blood cell DNA methylation of aging-related ubiquitination gene DZIP3 can predict the onset of early stage colorectal cancer. Frontiers in Oncology, 10, 544330.

Liang, T., Zhou, X., Li, P., You, G., Wang, F., Wang, P., & Feng, E. (2020). DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas. Aging (Albany NY), 12(24), 24995.

Oikawa, D., Shiota, M., Tokunaga, F., & Wanibuchi, H. (2018). Generation of rat monoclonal antibodies specific for DZIP3. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 37(3), 153-157.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Alternative Versions

Mouse Anti-DZIP3 Recombinant Antibody (3A1)

Related Products

Mouse Anti-DZIP3 Recombinant Antibody (D2037)

Mouse Anti-DZIP3 Recombinant Antibody (3A1)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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