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Mouse Anti-DZIP3 Recombinant Antibody (3A1) (V2LY-0425-LY1169)

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Datasheet
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal
Mouse
Clone
3A1
Application
WB, ELISA
Immunogen
DZIP3 (aa1021-1120) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
DAZ Interacting Zinc Finger Protein 3
Entrez Gene ID
9666
UniProt ID
Q86Y13
Research Area
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
Biological Process
Protein polyubiquitination Source: UniProtKB
Cellular Location
Cytoplasm

Kolapalli, S. P., Sahu, R., Chauhan, N. R., Jena, K. K., Mehto, S., Das, S. K., ... & Chauhan, S. (2021). RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer ProgressionDZIP3 Is a Novel Driver of Cell-Cycle and Cancer Progression. Cancer research, 81(2), 315-331.

Mamoor, S. (2021). DZIP3 is a differentially expressed gene in human metastatic breast cancer, in the brain and in the lymph nodes.

Quan, Y., Liang, F., Wu, D., Yao, X., Hu, Z., Zhu, Y., ... & Xiong, J. (2020). Blood cell DNA methylation of aging-related ubiquitination gene DZIP3 can predict the onset of early stage colorectal cancer. Frontiers in Oncology, 10, 544330.

Liang, T., Zhou, X., Li, P., You, G., Wang, F., Wang, P., & Feng, E. (2020). DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas. Aging (Albany NY), 12(24), 24995.

Oikawa, D., Shiota, M., Tokunaga, F., & Wanibuchi, H. (2018). Generation of rat monoclonal antibodies specific for DZIP3. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 37(3), 153-157.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Mouse Anti-DZIP3 Recombinant Antibody (D2037) (CAT#: CBMAB-D2037-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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