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Mouse Anti-EBF2 Recombinant Antibody (CBWJN-0808) (CBMAB-N0287-WJ)

This product is a Mouse antibody that recognizes EBF2. The antibody CBWJN-0808 can be used for immunoassay techniques such as: IHC, WB.
See all EBF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJN-0808
Antibody Isotype
IgG2a, κ
Application
IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.09% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
early B cell factor 2
Introduction
EBF2 (Early B Cell Factor 2) is a Protein Coding gene. The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family of non-basic, helix-loop-helix transcription factors that have a well conserved DNA binding domain. Diseases associated with EBF2 include Inguinal Hernia and Kallmann Syndrome.
Entrez Gene ID
UniProt ID
Alternative Names
COE2, EBF-2, O/E-3, OE-3
Research Area
Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).
Biological Process
Adipose tissue development Source: Ensembl
Brown fat cell differentiation Source: Ensembl
Cell fate determination Source: Ensembl
Positive regulation of chromatin binding Source: Ensembl
Positive regulation of cold-induced thermogenesis Source: YuBioLab
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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