Mouse Anti-ECH1 Recombinant Antibody (CBFYE-0406) (CBMAB-E0718-FY)

Name: Mouse Anti-ECH1 Recombinant Antibody (CBFYE-0406)
SKU: CBMAB-E0718-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYE-0406

Application

WB, IP, IF, ELISA

Specificity

Mouse, Rat, Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

enoyl Coenzyme A hydratase 1, peroxisomal

Introduction

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Entrez Gene ID

Human	1891
Mouse	51798
Rat	64526

UniProt ID

Human	Q13011
Mouse	O35459
Rat	Q62651

Alternative Names

Enoyl-CoA Hydratase 1; Delta3,5-Delta2,4-Dienoyl-Coenzyme A Isomerase; Enoyl Coenzyme A Hydratase 1, Peroxisomal; Enoyl-CoA Hydratase 1, Peroxisomal; Peroxisomal Enoyl-CoA Hydratase 1; Delta(3,5)-Delta(2,4)-Dienoyl-CoA Isomerase, Mitochondrial

Research Area

Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.

Biological Process

Fatty acid beta-oxidation Source: UniProtKB-UniPathway

Cellular Location

Mitochondrion; Peroxisome

Dao, C. K., Kenaston, A., Hirasaka, K., Kohno, S., Riley, C., Fang, G., ... & Mills, E. M. (2019). Identification of a fatty acid-sensitive interaction between mitochondrial uncoupling protein 3 and enoyl-CoA hydratase 1 in skeletal muscle. bioRxiv, 821637.

Sharma, N. K., Chuang Key, C. C., Civelek, M., Wabitsch, M., Comeau, M. E., Langefeld, C. D., ... & Das, S. K. (2019). Genetic regulation of Enoyl-CoA hydratase domain-containing 3 in adipose tissue determines insulin sensitivity in African Americans and Europeans. Diabetes, 68(7), 1508-1522.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-ECH1 Recombinant Antibody (CBFYE-0406) (CAT#: V2LY-0425-LY1335)

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Mouse Anti-ECH1 Recombinant Antibody (CBFYE-0406) (CAT#: V2LY-0425-LY1335)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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