ECH1

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq]
Full Name
enoyl Coenzyme A hydratase 1, peroxisomal
Research Area
Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA.
Biological Process
Fatty acid beta-oxidation Source: UniProtKB-UniPathway
Cellular Location
Mitochondrion; Peroxisome
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Anti-ECH1 antibodies

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Mouse Anti-ECH1 Monoclonal Antibody (5G8) (CBMAB-1122-YC)

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Target: ECH1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 5G8
Application*: E, WB
Datasheet SDS

Human Recombinant ECH1 protein, His Tag (V2LY-0526-LY3680)

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Target: ECH1
Expressed Host: E. coli
Sequence: Amino Acid: 34-328
Tag: His Tag
Datasheet SDS

Mouse Anti-ECH1 Recombinant Antibody (CBFYE-0406) (V2LY-0425-LY1335)

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Target: ECH1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat, Human
Clone: CBFYE-0406
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-ECH1 Recombinant Antibody (5G8) (V2LY-0425-LY1334)

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Target: ECH1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 5G8
Application*: E, WB
Datasheet SDS

Mouse Anti-ECH1 Recombinant Antibody (CBFYE-0406) (CBMAB-E0718-FY)

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Target: ECH1
Host: Mouse
Specificity: Mouse, Rat, Human
Clone: CBFYE-0406
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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