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Mouse Anti-EID3 Recombinant Antibody (2E5) (CBMAB-A2514-LY)

The product is antibody recognizes EID3. The antibody 2E5 immunoassay techniques such as: WB, ELISA.
See all EID3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E5
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
EID3 (NP_001008395.1, 1 a.a. ~ 333 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
EP300 interacting inhibitor of differentiation 3
Entrez Gene ID
493861
UniProt ID
Q8N140
Alternative Names
FLJ25832; NSE4B; NSMCE4B
Research Area
Tissue-specific component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components.

Acts as a repressor of nuclear receptor-dependent transcription possibly by interfering with CREBBP-dependent coactivation. May function as a coinhibitor of other CREBBP/EP300-dependent transcription factors.
Biological Process
DNA recombination Source: UniProtKB-KW
DNA repair Source: GO_Central
Cellular Location
Nucleus; Cytoplasm; Telomere. May shuttle between nucleus and cytoplasm.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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