Rabbit Anti-KDELR3 Recombinant Antibody (EG1135) (CBMAB-EN1352-LY)

Name: Rabbit Anti-KDELR3 Recombinant Antibody (EG1135)
SKU: CBMAB-EN1352-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1135

Application

WB: 1:500~1:1000 ELISA: 1:20000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human ERD23.

Specificity

Human, Mouse

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Kdel Endoplasmic Reticulum Protein Retention Receptor 3

Entrez Gene ID

Human	11015
Mouse	105785

UniProt ID

Human	O43731
Mouse	Q8R1L4

Function

Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum.

Biological Process

Endoplasmic reticulum to Golgi vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Protein retention in ER lumenManual Assertion Based On ExperimentIBA:GO_Central
Protein transportIEA:UniProtKB-KW
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Endoplasmic reticulum membrane; Golgi apparatus membrane; Cytoplasmic vesicle, COPI-coated vesicle membrane. Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.

Topology

Lumenal: 1-4
Helical: 5-24
Cytoplasmic: 25-32
Helical: 33-52
Lumenal: 53-58
Helical: 59-79
Cytoplasmic: 80-92
Helical: 93-110
Lumenal: 111-116
Helical: 117-135
Cytoplasmic: 136-149
Helical: 150-168
Lumenal: 169-178
Helical: 179-199
Cytoplasmic: 200-214

Altenhofen, D., Khuong, J. M. A., Kuhn, T., Lebek, S., Görigk, S., Kaiser, K., ... & Al-Hasani, H. (2023). E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice. International Journal of Molecular Sciences, 24(1), 845.

Zhang, J., Zhang, J., Guan, J., Yu, L., & Yan, S. (2022). KDELR3 Is a Prognostic Biomarker Related to the Immune Infiltration and Chemoresistance of Anticancer Drugs in Uveal Melanoma. Disease Markers, 2022.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-KDELR3 Recombinant Antibody (KD10-2) (CAT#: CBMAB-K0655-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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