Mouse Anti-ETV7 Monoclonal Antibody (1A1) (V2LY-0825-LY890)

Name: Mouse Anti-ETV7 Monoclonal Antibody (1A1)
SKU: V2LY-0825-LY890
Rating: 5 (1 reviews)

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Published Data

Mouse Anti-ETV7 Monoclonal Antibody (1A1) (V2LY-0825-LY890) in WB

(A) Representative Western blots of PI3K, AKT, p-AKT(Ser473), mTOR, and ETV7 in control (C) and VD3-GNP-treated MDA-MB-231 cells. * p < 0.05. (B) Calculation of the protein expression (band density) in Western blot analysis (n = 3) in MDA-MB-231 cells. Protein levels of PI3K, AKT, p-AKT (Ser473), mTOR, and ETV7 were normalized by β-actin, * p < 0.05, ** p < 0.001. (C) representative Western blots of PI3K, AKT, p-AKT (Ser473), mTOR, and ETV7 in control (C), and VD3-GNP-treated MCF-7 cells. β-actin was used as a loading control. (D) The protein expression (band density) in Western blot analysis (n = 3) for protein levels in MCF-7 cells was normalized by β-actin, * p < 0.05, ** p < 0.001. ...View More

Roy, M., & Hussain, F. (2024). Mitigation of Breast Cancer Cells' Invasiveness via Down Regulation of ETV7, Hippo, and PI3K/mTOR Pathways by Vitamin D3 Gold-Nanoparticles. International Journal of Molecular Sciences, 25(10), 5348.

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

1A1

Application

Immunogen

Recombinant protein

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Supernatant

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

ETV7

Entrez Gene ID

51513

UniProt ID

Q9Y603

Research Area

Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.

Biological Process

Animal organ morphogenesis Source: ProtInc
Cell differentiation Source: GO_Central
Negative regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Transcription by RNA polymerase II Source: ProtInc

Cellular Location

Nucleus

Froggatt, H. M., Harding, A. T., Chaparian, R. R., & Heaton, N. S. (2021). ETV7 limits antiviral gene expression and control of influenza viruses. Science signaling, 14(691), eabe1194.

Li, H., Zhang, Y., & Zheng, S. (2021). Comprehensive Analysis Identified ETV7 as a Potential Prognostic Biomarker in Bladder Cancer. BioMed research international, 2021.

Froggatt, H. M., Harding, A. T., Heaton, B. E., & Heaton, N. S. (2020). ETV7 limits antiviral gene expression and control of SARS-CoV-2 and influenza viruses. bioRxiv, 851543.

Qu, H., Zhao, H., Zhang, X., Liu, Y., Li, F., Sun, L., & Song, Z. (2020). Integrated analysis of the ETS family in melanoma reveals a regulatory role of ETV7 in the immune microenvironment. Frontiers in immunology, 11, 612784.

Alessandrini, F., Pezzè, L., Menendez, D., Resnick, M. A., & Ciribilli, Y. (2018). ETV7-mediated DNAJC15 repression leads to doxorubicin resistance in breast cancer cells. Neoplasia, 20(8), 857-870.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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