Mouse Anti-F2RL2 Recombinant Antibody (EG1161) (V2LY-0825-LY1106)

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Basic Information

Host Animal
Mouse
Clone
EG1161
Application
WB, IP, FC
Immunogen
Amino acids 31-47 of human PAR-3.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, gelatin
Preservative
Sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
More Infomation

Target

Full Name
Coagulation Factor II Thrombin Receptor Like 2
Entrez Gene ID
UniProt ID
Research Area
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Biological Process
Blood coagulation Source: ProtInc
Platelet activation Source: Reactome
Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling Pathway Source: GO_Central
Positive regulation of Rho protein signal transduction Source: GO_Central
Response to wounding Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 39-94
Helical: 95-120
Cytoplasmic: 121-128
Helical: 129-148
Extracellular: 149-167
Helical: 168-189
Cytoplasmic: 190-206
Helical: 207-230
Extracellular: 231-260
Helical: 261-280
Cytoplasmic: 281-297
Helical: 298-322
Extracellular: 323-336
Helical: 337-361
Cytoplasmic: 362-374
PTM
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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