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Mouse Anti-FAM162A Recombinant Antibody (CBFYH-0188) (CBMAB-H1065-FY)

This product is mouse antibody that recognizes FAM162A. The antibody CBFYH-0188 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all FAM162A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-0188
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Family With Sequence Similarity 162 Member A
Introduction
FAM162A (Family With Sequence Similarity 162 Member A) is a Protein Coding gene. An important paralog of this gene is FAM162B.
Entrez Gene ID
26355
UniProt ID
Q96A26
Alternative Names
Family With Sequence Similarity 162 Member A; Growth And Transformation-Dependent Protein; E2-Induced Gene 5 Protein; C3orf28; HGTD-P; E2IG5
Research Area
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues (PubMed:15082785).

May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition (PubMed:15082785).

May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly (By similarity).
Biological Process
Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Cellular response to hypoxia Source: UniProtKB
Neuron apoptotic process Source: GO_Central
Positive regulation of apoptotic process Source: UniProtKB
Positive regulation of release of cytochrome c from mitochondria Source: UniProtKB
Cellular Location
Mitochondrion membrane
Topology
Helical: 103-120
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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