Mouse Anti-FAM162A Recombinant Antibody (CBFYH-0188) (CBMAB-H1065-FY)

Name: Mouse Anti-FAM162A Recombinant Antibody (CBFYH-0188)
SKU: CBMAB-H1065-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0188

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 120-139 near the C-terminus of human HGTD-P.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Family With Sequence Similarity 162 Member A

Introduction

FAM162A (Family With Sequence Similarity 162 Member A) is a Protein Coding gene. An important paralog of this gene is FAM162B.

Entrez Gene ID

26355

UniProt ID

Q96A26

Alternative Names

Family With Sequence Similarity 162 Member A; Growth And Transformation-Dependent Protein; E2-Induced Gene 5 Protein; C3orf28; HGTD-P; E2IG5

Research Area

Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues (PubMed:15082785).

May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition (PubMed:15082785).

May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly (By similarity).

Biological Process

Activation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
Cellular response to hypoxia Source: UniProtKB
Neuron apoptotic process Source: GO_Central
Positive regulation of apoptotic process Source: UniProtKB
Positive regulation of release of cytochrome c from mitochondria Source: UniProtKB

Cellular Location

Mitochondrion membrane

Topology

Helical: 103-120

Muñoz Quezada, M. H. (2019). Estudio funcional de la proteína mitocondrial FAM162A sobre la morfología y bioenergética de las mitocondrias y su rol en la mitofagia (Doctoral dissertation, Universidad Andrés Bello).

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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