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Mouse Anti-FBXL8 Recombinant Antibody (2E1) (CBMAB-A2878-LY)

The product is antibody recognizes FBXL8. The antibody 2E1 immunoassay techniques such as: sELISA, ELISA.
See all FBXL8 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2E1
Antibody Isotype
IgG1, κ
Application
sELISA, ELISA

Basic Information

Immunogen
FBXL8 (AAH14414, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
F-box and leucine-rich repeat protein 8
Introduction
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq]
Entrez Gene ID
55336
UniProt ID
Q96CD0
Alternative Names
FBL8; FLJ11278; MGC19959
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Biological Process
Entrainment of circadian clock by photoperiod Source: GO_Central
G2/M transition of mitotic cell cycle Source: GO_Central
Regulation of cell cycle Source: GO_Central
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: GO_Central
Cellular Location
Cytosol; Nucleus; SCF ubiquitin ligase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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