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Rat Anti-FCGR1 Recombinant Antibody (CBFYC-2667) (CBMAB-C2741-FY)

This product is rat antibody that recognizes FCGR1. The antibody CBFYC-2667 can be used for immunoassay techniques such as: FC.
See all FCGR1 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYC-2667
Antibody Isotype
IgG2a
Application
FC

Basic Information

Immunogen
NS0-derived recombinant mouse Fc gamma RI extracellular domain Glu25-Pro297
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 5% trehalose
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FC RECEPTOR, IGG, HIGH AFFINITY
Introduction
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Entrez Gene ID
14129
UniProt ID
P26151
Alternative Names
CD64; IGGHAFC; AI323638; AV092959; FcgammaRI
Research Area
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Innate immune response Source: UniProtKB-KW
Phagocytosis, engulfment Source: ProtInc
Positive regulation of protein tyrosine kinase activity Source: ARUK-UCL
Regulation of immune response Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Cell membrane. Stabilized at the cell membrane through interaction with FCER1G.
Topology
Extracellular: 16-292
Helical: 293-313
Cytoplasmic: 314-374
PTM
Phosphorylated on serine residues.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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