FCGR1A

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
Full Name
Fc Fragment Of IgG Receptor Ia
Alternative Names
Fc Fragment Of IgG Receptor Ia; Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64); Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64); Fc Gamma Receptor Ia; IgG Fc Receptor I; Fc-Gamma RIA; Fc-Gamma RI; FcgammaRIa; IGFR1;
Research Area
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Innate immune response Source: UniProtKB-KW
Phagocytosis, engulfment Source: ProtInc
Positive regulation of protein tyrosine kinase activity Source: ARUK-UCL
Regulation of immune response Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Cell membrane. Stabilized at the cell membrane through interaction with FCER1G.
Topology
Extracellular: 16-292
Helical: 293-313
Cytoplasmic: 314-374
PTM
Phosphorylated on serine residues.
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Anti-FCGR1A antibodies

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Target: FCGR1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: AG69
Application*: B, F, C, In Vivo
In Vivo Assay Functional Assay
Target: FCGR1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4336
Application*: IH, F
Target: FCGR1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4518
Application*: WB
Target: FCGR1A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: 22
Application*: E
Target: FCGR1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-2667
Application*: F, IH
Target: FCGR1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-2666
Application*: E, P
Target: FCGR1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYC-0491
Application*: E, P
Target: FCGR1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYC-0119
Application*: E
Target: FCGR1A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 102
Application*: E
Target: FCGR1A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 407
Application*: F, IF
Target: FCGR1
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBXF-2553
Application*: WB
Target: FCGR1A
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Mouse
Clone: CBXF-3574
Application*: WB, IP, IF, E, P
Target: FCGR1A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2395
Application*: F
Target: FCGR1
Host: Human
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-2552
Application*: F
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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