Human FCGR1A ELISA Kit (V2LY-0626-LY4671)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.14 ng/mL
Detection Range
0.3-90 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
42.6 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Fc Fragment Of IgG Receptor Ia
Alternative Names
Fc Fragment Of IgG Receptor Ia; Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64); Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64); Fc Gamma Receptor Ia; IgG Fc Receptor I; Fc-Gamma RIA; Fc-Gamma RI; FcgammaRIa; IGFR1;
Research Area
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Innate immune response Source: UniProtKB-KW
Phagocytosis, engulfment Source: ProtInc
Positive regulation of protein tyrosine kinase activity Source: ARUK-UCL
Regulation of immune response Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Cell membrane. Stabilized at the cell membrane through interaction with FCER1G.
Topology
Extracellular: 16-292
Helical: 293-313
Cytoplasmic: 314-374
PTM
Phosphorylated on serine residues.

Wu, J., Li, Y., Rendahl, A., & Bhargava, M. (2022). Novel Human FCGR1A Variants Affect CD64 Functions and Are Risk Factors for Sarcoidosis. Frontiers in immunology, 13, 841099.

Reddy, J. S., Wang, X., Allen, M., Carrasquillo, M. M., Biernacka, J. M., Jenkins, G. D., ... & Younkin, S. G. (2022). Polygenic risk score analysis identifies deleterious protein-coding variants in novel immune pathway genes ATP8B4, FCGR1A, and LILRB1 that associate with Alzheimer's disease. medRxiv.

Xu, J. L., & Guo, Y. (2020). FCGR1A serves as a novel biomarker and correlates with immune infiltration in four cancer types. Frontiers in molecular biosciences, 7, 581615.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus, Rhesus Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY25)

Canine Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY1225)

Canine Recombinant FCGR1A protein, His Tag-1 (CAT#: V2LY-0526-LY1226)

Human Recombinant FCGR1A protein, ECD, His Tag (CAT#: V2LY-0526-LY2915)

Human Recombinant FCGR1A protein, ECD, His Tag-1 (CAT#: V2LY-0526-LY2916)

Human Recombinant FCGR1A protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY2917)

Mouse Recombinant FCGR1A protein, Biotin Conjugated, His & AVI Tag (CAT#: V2LY-0526-LY8054)

Mouse Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY8055)

Rabbit Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY9120)

Rat Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY9260)

Antibody Pairs

FCGR1A Matched Antibody Pair (418) (CAT#: APMAB-418LY)

FCGR1A Matched Antibody Pair (419) (CAT#: APMAB-419LY)

Related Products

Cynomolgus, Rhesus Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY25)

Rabbit Anti-FCGR1A Recombinant Antibody (CBFYC-2666) (CAT#: CBMAB-C2740-FY)

Canine Recombinant FCGR1A protein, His Tag-1 (CAT#: V2LY-0526-LY1226)

Mouse Anti-FCGR1A Recombinant Antibody (CBXF-3574) (CAT#: CBMAB-F2080-CQ)

Mouse Anti-FCGR1A Recombinant Antibody (CBXF-2395) (CAT#: CBMAB-F1988-CQ)

Rabbit Anti-FCGR1A Recombinant Antibody (CBFYC-0491) (CAT#: CBMAB-C0541-FY)

Rabbit Anti-FCGR1A Recombinant Antibody (CBFYC-0119) (CAT#: CBMAB-C0136-FY)

Rat Recombinant FCGR1A protein, His Tag (CAT#: V2LY-0526-LY9260)

Mouse Anti-FCGR1A Recombinant Antibody (CBT4336) (CAT#: V2LY-0625-LY1006)

Rabbit Anti-FCGR1A Recombinant Antibody (407) (CAT#: CBMAB-C6447-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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