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Rat Anti-FCGR1 Recombinant Antibody (CBXF-2552) (CBMAB-F0015-CQ)

This product is a rat antibody that recognizes FCGR1. The antibody CBXF-2552 can be used for immunoassay techniques such as: FC, CyTOF.
See all FCGR1 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBXF-2552
Antibody Isotype
IgG2a
Application
FC, CyTOF

Basic Information

Immunogen
NS0-derived recombinant mouse Fc gamma RI extracellular domain, Glu25-Pro297
Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with trehalose
Concentration
LYOPH
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FC RECEPTOR, IGG, HIGH AFFINITY
Entrez Gene ID
14129
UniProt ID
P26151
Alternative Names
Fc Fragment Of IgG Receptor Ia; Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64); Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64); Fc Gamma Receptor Ia; IgG Fc Receptor I; Fc-Gamma RIA; Fc-Gamma RI; FcgammaRIa; IGFR1;
Research Area
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune response Source: ProtInc
Innate immune response Source: UniProtKB-KW
Phagocytosis, engulfment Source: ProtInc
Positive regulation of protein tyrosine kinase activity Source: ARUK-UCL
Regulation of immune response Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Cell membrane. Stabilized at the cell membrane through interaction with FCER1G.
Topology
Extracellular: 16-292
Helical: 293-313
Cytoplasmic: 314-374
PTM
Phosphorylated on serine residues.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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