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Mouse Anti-FOXP4 Antibody (1A10) (CBMAB-0395-YC)

Provided herein are mouse monoclonal antibodies against Human FOXP4. The antibody clone 1A10 can be used for immunoassay techniques, such as IP and MA.
See all FOXP4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A10
Antibody Isotype
IgG1
Application
IP, MA

Basic Information

Immunogen
Recombinant peptide
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
FOXP4
Introduction
Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. FOXP4 (forkhead box P4) belongs to subfamily P of the forkhead box (FOX) transcription factor family. FOXP4 may play a role in the development of tumors of the kidney and larynx.
Entrez Gene ID
116113
UniProt ID
Q8IVH2
Alternative Names
FLJ40908
Function
Transcriptional repressor that represses lung-specific expression.
Biological Process
Negative regulation of transcription by RNA polymerase II Source: GO_Central
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus

Xue, P., Huang, S., Han, X., Zhang, C., Yang, L., Xiao, W., ... & Zhou, Y. (2022). Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2. Cell Death & Differentiation, 29(1), 82-95.

Yang, L., Liu, Z., Ma, J., Wang, H., Gao, D., Zhang, C., & Ma, Q. (2021). CircRPPH1 serves as a sponge for miR-296-5p to enhance progression of breast cancer by regulating FOXP4 expression. American Journal of Translational Research, 13(7), 7556.

Zhao, J., Yang, T., & Li, L. (2020). LncRNA FOXP4-AS1 is involved in cervical cancer progression via regulating miR-136-5p/CBX4 axis. OncoTargets and therapy, 13, 2347.

Liang, H., Huang, H., Li, Y., Lu, Y., & Ye, T. (2020). CircRNA_0058063 functions as a ceRNA in bladder cancer progression via targeting miR-486-3p/FOXP4 axis. Bioscience Reports, 40(3).

Wang, X., Liu, L., Zhao, W., Li, Q., Wang, G., & Li, H. (2020). LncRNA SNHG16 promotes the progression of laryngeal squamous cell carcinoma by mediating miR-877-5p/FOXP4 axis. OncoTargets and therapy, 13, 4569.

Li, Y., Li, T., Yang, Y., Kang, W., Dong, S., & Cheng, S. (2020). YY1‐induced upregulation of FOXP4‐AS1 and FOXP4 promote the proliferation of esophageal squamous cell carcinoma cells. Cell biology international, 44(7), 1447-1457.

Huang, C., Deng, H., Wang, Y., Jiang, H., Xu, R., Zhu, X., ... & Zhao, X. (2019). Circular RNA circABCC4 as the ceRNA of miR‐1182 facilitates prostate cancer progression by promoting FOXP4 expression. Journal of cellular and molecular medicine, 23(9), 6112-6119.

Wu, X., Xiao, Y., Zhou, Y., Zhou, Z., & Yan, W. (2019). LncRNA FOXP4-AS1 is activated by PAX5 and promotes the growth of prostate cancer by sequestering miR-3184-5p to upregulate FOXP4. Cell death & disease, 10(7), 472.

Zhang, G., & Zhang, G. (2019). Upregulation of FoxP4 in HCC promotes migration and invasion through regulation of EMT. Oncology letters, 17(4), 3944-3951.

Xiong, Y., Zhang, J., & Song, C. (2019). CircRNA ZNF609 functions as a competitive endogenous RNA to regulate FOXP4 expression by sponging miR‐138‐5p in renal carcinoma. Journal of cellular physiology, 234(7), 10646-10654.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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