Mouse Anti-FOXS1 Recombinant Antibody (CBXF-1797) (V2LY-1225-LY69)

Name: Mouse Anti-FOXS1 Recombinant Antibody (CBXF-1797)
SKU: V2LY-1225-LY69
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-1797

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 115-270 mapping within an internal region of mouse FKHL18.

Host Species

Mouse

Specificity

Mouse, Rat

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Forkhead Box S1

Entrez Gene ID

Rat	311547
Mouse	14239

UniProt ID

Rat	Q5HZE9
Mouse	Q61574

Function

Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity).

Biological Process

Anatomical structure morphogenesis Source: GO_Central
Blood vessel development Source: UniProtKB
Cell differentiation Source: GO_Central
Negative regulation of DNA-binding transcription factor activity Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Neuromuscular process controlling balance Source: Ensembl
Positive regulation of multicellular organism growth Source: Ensembl
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

Bévant, K., Desoteux, M., Angenard, G., Pineau, R., Caruso, S., Louis, C., ... & Coulouarn, C. (2022). TGFβ‐induced FOXS1 controls epithelial–mesenchymal transition and predicts a poor prognosis in liver cancer. Hepatology Communications, 6(5), 1157-1171.

Liu, Y., Tu, M., & Wang, L. (2022). Pan-cancer analysis predicts FOXS1 as a key target in prognosis and tumor immunotherapy. International Journal of General Medicine, 2171-2185.

Xue, B. Z., Xiang, W., Zhang, Q., Wang, H. F., Zhou, Y. J., Tian, H., ... & Fu, P. (2021). CD90 low glioma-associated mesenchymal stromal/stem cells promote temozolomide resistance by activating FOXS1-mediated epithelial-mesenchymal transition in glioma cells. Stem Cell Research & Therapy, 12, 1-11.

Wang, S., Ran, L., Zhang, W., Leng, X., Wang, K., Liu, G., ... & Song, F. (2019). FOXS1 is regulated by GLI1 and miR-125a-5p and promotes cell proliferation and EMT in gastric cancer. Scientific Reports, 9(1), 5281.

Lu, Q., Ma, X., Li, Y., Song, W., Zhang, L., Shu, Y., & Wan, B. (2019). Overexpression of FOXS1 in gastric cancer cell lines inhibits proliferation, metastasis, and epithelial‐mesenchymal transition of tumor through downregulating wnt/β‐catenin pathway. Journal of Cellular Biochemistry, 120(3), 2897-2907.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-FOXS1 Recombinant Antibody (CBXF-1797) (CAT#: CBMAB-F3332-CQ)

Related Products

Mouse Anti-FOXS1 Recombinant Antibody (CBXF-1797) (CAT#: CBMAB-F3332-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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