Mouse Anti-FSCN2 Recombinant Antibody (CBXF-1802) (V2LY-1225-LY133)

Name: Mouse Anti-FSCN2 Recombinant Antibody (CBXF-1802)
SKU: V2LY-1225-LY133
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-1802

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 380-492 mapping at the C-terminus of human Fascin 2.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG1, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Fascin Actin-Bundling Protein 2, Retinal

Entrez Gene ID

25794

UniProt ID

O14926

Function

Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.

Biological Process

Actin cytoskeleton organization Source: UniProtKB
Actin filament bundle assembly Source: GO_Central
Anatomical structure morphogenesis Source: ProtInc
Cell migration Source: GO_Central
Establishment or maintenance of cell polarity Source: GO_Central
Eye photoreceptor cell development Source: Ensembl
Visual perception Source: ProtInc

Cellular Location

Cytoskeleton; Stereocilium

Involvement in disease

Retinitis pigmentosa 30 (RP30):
A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Gui, W., Nusinowitz, S., & Sarraf, D. (2018). Novel cone dystrophy with central ellipsoid zone loss associated with human retinal fascin gene (Fscn2) mutation. Retinal Cases and Brief Reports, 12, S63-S66.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-FSCN2 Recombinant Antibody (CBXF-1802) (CAT#: CBMAB-F3337-CQ)

Related Products

Mouse Anti-FSCN2 Recombinant Antibody (CBXF-1802) (CAT#: CBMAB-F3337-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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