Mouse Anti-FUCA2 Recombinant Antibody (CBXF-3233) (V2LY-1225-LY255)

Name: Mouse Anti-FUCA2 Recombinant Antibody (CBXF-3233)
SKU: V2LY-1225-LY255
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXF-3233

Application

WB, IP, IF, ELISA

Immunogen

Amino acids 307-338 mapping within an internal region of human FUCA2.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

Application	Note
ELISA	1:100-1:1,000
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, gelatin

Preservative

Sodium azide

Concentration

0.2 mg/ml

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

fucosidase, alpha-L- 2, plasma

Entrez Gene ID

2519

UniProt ID

Q9BTY2

Function

Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

Biological Process

Fucose metabolic process Source: UniProtKB
Glycoside catabolic process Source: UniProtKB
Regulation of entry of bacterium into host cell Source: UniProtKB
Response to bacterium Source: UniProtKB

Cellular Location

Secreted

Liu, Q., Dong, H. T., Zhao, T., Yao, F., Xu, Y., Chen, B., ... & Xing, P. (2022). Cancer-associated adipocytes release FUCA2 to promote aggressiveness in TNBC. Endocrine-Related Cancer, 29(3), 139-149.

Quirino, M. W. L., de Barros Albuquerque, A. P., de Souza, M. D. F. D., da Silva Filho, A. F., Martins, M. R., da Rocha Pitta, M. G., ... & de Melo, M. J. B. (2022). FUCA2 and TSTA3 expression in gastric cancer: candidate biomarkers of malignant transformation. Folia Histochemica et Cytobiologica, 60(4), 335-343.

Zhong, A., Chen, T., Xing, Y., Pan, X., & Shi, M. (2021). FUCA2 is a prognostic biomarker and correlated with an immunosuppressive microenvironment in pan-cancer. Frontiers in immunology, 12, 758648.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-FUCA2 Recombinant Antibody (CBXF-3233) (CAT#: CBMAB-F3928-CQ)

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Mouse Anti-FUCA2 Recombinant Antibody (CBXF-3233) (CAT#: CBMAB-F3928-CQ)

Mouse Anti-FUCA2 Recombinant Antibody (CBXF-1810) (CAT#: CBMAB-F3345-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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