Rabbit Anti-GAD2 Recombinant Antibody (CBLG1-481) (V2LY-1225-LY585)

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Basic Information

Host Animal
Rabbit
Clone
CBLG1-481
Application
IHC
Immunogen
Purified recombinant fragment of human GAD2/GAD65 (aa 1-100) expressed in E. Coli.
Host Species
Rabbit
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
ApplicationNote
IHC-P1-2 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, BSA
Preservative
Sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Glutamate Decarboxylase 2
Entrez Gene ID
UniProt ID
Function
Catalyzes the production of GABA.
Biological Process
Chemical synaptic transmission Source: ProtInc
Glutamate decarboxylation to succinate Source: ProtInc
Neurotransmitter biosynthetic process Source: UniProtKB-KW
Response to drug Source: Ensembl
Cellular Location
Cytosol; Presynaptic cell membrane; Golgi apparatus membrane; Cytoplasmic vesicle. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
PTM
Phosphorylated; which does not affect kinetic parameters or subcellular location.
Palmitoylated; which is required for presynaptic clustering.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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