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Mouse Anti-GADD45G Recombinant Antibody (CBFYC-2713) (CBMAB-C2787-FY)

This product is mouse antibody that recognizes GADD45G. The antibody CBFYC-2713 can be used for immunoassay techniques such as: FC, IF, WB.
See all GADD45G antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-2713
Antibody Isotype
IgG1
Application
FC, IF, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
growth arrest and DNA damage inducible gamma
Introduction
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Entrez Gene ID
10912
UniProt ID
O95257
Alternative Names
Growth Arrest And DNA Damage Inducible Gamma; DNA Damage-Inducible Transcript 2 Protein; Cytokine-Responsive Protein CR6; Gadd-Related Protein, 17 KD; DDIT-2; DDIT2; CR6
Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Biological Process
Activation of MAPKKK activity Source: UniProtKB
Apoptotic process Source: UniProtKB-KW
Cell differentiation Source: UniProtKB-KW
Positive regulation of apoptotic process Source: UniProtKB
Positive regulation of cold-induced thermogenesis Source: YuBioLab
Positive regulation of JNK cascade Source: UniProtKB
Positive regulation of p38MAPK cascade Source: UniProtKB
Regulation of cell cycle Source: GO_Central
Cellular Location
Nucleus; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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