Mouse Anti-GALR2 Recombinant Antibody (G0163) (V2LY-1225-LY632)

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Basic Information

Host Animal
Mouse
Clone
G0163
Application
WB, IHC
Immunogen
Human GalR2.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
ApplicationNote
WB1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
galanin receptor 2
Entrez Gene ID
UniProt ID
Function
Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231).

The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: Ensembl
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Cell surface receptor signaling pathway Source: ProtInc
Feeding behavior Source: ProtInc
Galanin-activated signaling pathway Source: GO_Central
Inositol phosphate metabolic process Source: Ensembl
Learning or memory Source: ProtInc
Multicellular organism development Source: ProtInc
Muscle contraction Source: ProtInc
Negative regulation of adenylate cyclase activity Source: InterPro
Neuron projection development Source: Ensembl
Neuropeptide signaling pathway Source: GO_Central
Phosphatidylinositol metabolic process Source: Ensembl
Phospholipase C-activating G protein-coupled receptor signaling pathway Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: ProtInc
Positive regulation of large conductance calcium-activated potassium channel activity Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 1-28
Helical: 29-49
Cytoplasmic: 50-60
Helical: 61-81
Extracellular: 82-99
Helical: 100-121
Cytoplasmic: 122-141
Helical: 142-162
Extracellular: 163-187
Helical: 188-208
Cytoplasmic: 209-237
Helical: 238-258
Extracellular: 259-260
Helical: 261-281
Cytoplasmic: 282-387
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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