Rabbit Anti-GALR3 Recombinant Antibody (EG1282) (CBMAB-EN1546-LY)

Name: Rabbit Anti-GALR3 Recombinant Antibody (EG1282)
SKU: CBMAB-EN1546-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rabbit

Clone

EG1282

Application

IF: 1:100~1:500 ELISA: 1:40000

Immunogen

The antibody was produced against synthesized peptide derived from internal of human GALR3.

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Galanin Receptor 3

Introduction

The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]

Entrez Gene ID

8484

UniProt ID

O60755

Alternative Names

Galanin Receptor 3; GAL3-R; GALR-3; Galanin Receptor, Family Member 3; Galanin Receptor Type 3; GALNR3;

Function

Receptor for the hormone galanin (PubMed:25691535).

Receptor for the hormone spexin-1 (PubMed:24517231).

Biological Process

Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Chemical synaptic transmission Source: ProtInc
Feeding behavior Source: ProtInc
Galanin-activated signaling pathway Source: GO_Central
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: GO_Central
Learning or memory Source: ProtInc
Negative regulation of adenylate cyclase activity Source: InterPro
Neuropeptide signaling pathway Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 1-20
Helical: 21-41
Cytoplasmic: 42-57
Helical: 58-78
Extracellular: 79-96
Helical: 97-118
Cytoplasmic: 119-138
Helical: 139-159
Extracellular: 160-184
Helical: 185-205
Cytoplasmic: 206-236
Helical: 237-257
Extracellular: 258-259
Helical: 260-280
Cytoplasmic: 281-368

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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