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Rabbit Anti-GALR3 Recombinant Antibody (EG1282) (CBMAB-EN1546-LY)

The product is antibody recognizes GALR3. The antibody EG1282 immunoassay techniques such as: IF: 1:100~1:500 ELISA: 1:40000.
See all GALR3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1282
Antibody Isotype
IgG
Application
IF: 1:100~1:500 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GALR3.
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Galanin Receptor 3
Introduction
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]
Entrez Gene ID
8484
UniProt ID
O60755
Alternative Names
Galanin Receptor 3; GAL3-R; GALR-3; Galanin Receptor, Family Member 3; Galanin Receptor Type 3; GALNR3;
Function
Receptor for the hormone galanin (PubMed:25691535).

Receptor for the hormone spexin-1 (PubMed:24517231).
Biological Process
Adenylate cyclase-modulating G protein-coupled receptor signaling pathway Source: GO_Central
Chemical synaptic transmission Source: ProtInc
Feeding behavior Source: ProtInc
Galanin-activated signaling pathway Source: GO_Central
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger Source: GO_Central
Learning or memory Source: ProtInc
Negative regulation of adenylate cyclase activity Source: InterPro
Neuropeptide signaling pathway Source: GO_Central
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 1-20
Helical: 21-41
Cytoplasmic: 42-57
Helical: 58-78
Extracellular: 79-96
Helical: 97-118
Cytoplasmic: 119-138
Helical: 139-159
Extracellular: 160-184
Helical: 185-205
Cytoplasmic: 206-236
Helical: 237-257
Extracellular: 258-259
Helical: 260-280
Cytoplasmic: 281-368
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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