Mouse Anti-GAS8 Recombinant Antibody (CBLG1-2596) (V2LY-1225-LY711)
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Basic Information
| Application | Note |
| ELISA | 1:100-1:1,000 |
| WB | 1:100-1:1,000 |
| IP | 1-2 µg per 100-500 µg of total protein (1 ml of cell lysate) |
| IF(ICC) | 1:50-1:500 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning (PubMed:26387594, PubMed:27120127, PubMed:27472056).
Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner (By similarity).
Cellular protein localization Source: GO_Central
Cilium movement involved in cell motility Source: GO_Central
Flagellated sperm motility Source: UniProtKB
Negative regulation of cell population proliferation Source: ProtInc
Positive regulation of protein localization to cilium Source: UniProtKB
Positive regulation of smoothened signaling pathway Source: UniProtKB
Regulation of microtubule binding Source: UniProtKB
A form of primary ciliary dyskinesia, a disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. CILD33 inheritance is autosomal recessive.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Alternative Versions
Mouse Anti-GAS8 Recombinant Antibody (CBLG1-2596) (CAT#: CBMAB-G2162-LY)
Related Products
Mouse Anti-GAS8 Recombinant Antibody (CBLG1-2595) (CAT#: V2LY-1225-LY712)
Rabbit Anti-GAS8 Recombinant Antibody (CBLG1-2595) (CAT#: CBMAB-G2161-LY)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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