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Rat Anti-GBGT1 Recombinant Antibody (117C9) (CBMAB-G2406-LY)

This product is antibody recognizes GBGT1. The antibody 117C9 immunoassay techniques such as: IHC-F.
See all GBGT1 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
117C9
Antibody Isotype
IgM
Application
IHC-F

Basic Information

Specificity
Mouse
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
Introduction
This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Entrez Gene ID
227671
UniProt ID
Q8VI38
Alternative Names
Fgs; Fs
Function
Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG) (PubMed:10506200).

Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure.
Biological Process
Carbohydrate metabolic process Source: InterPro
Glycolipid biosynthetic process Source: ProtInc
Lipid glycosylation Source: GO_Central
Protein glycosylation Source: UniProtKB-UniPathway
Cellular Location
Golgi apparatus membrane
Topology
Cytoplasmic: 1-5
Helical: 6-26
Lumenal: 27-347
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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