Rat Anti-GBGT1 Recombinant Antibody (117C9) (CBMAB-G2406-LY)

Name: Rat Anti-GBGT1 Recombinant Antibody (117C9)
SKU: CBMAB-G2406-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Rat

Clone

117C9

Application

IHC-F

Specificity

Mouse

Antibody Isotype

IgM

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

globoside alpha-1,3-N-acetylgalactosaminyltransferase 1

Introduction

This gene encodes a glycosyltransferase that plays a role in the synthesis of Forssman glycolipid (FG), a member of the globoseries glycolipid family. Glycolipids such as FG form attachment sites for the binding of pathogens to cells; expression of this protein may determine host tropism to microorganisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Entrez Gene ID

227671

UniProt ID

Q8VI38

Alternative Names

Fgs; Fs

Function

Has lost the ability to synthesize Forssman glycolipid antigen (FORS1/FG) (PubMed:10506200).

Might have acquired an alternative function in glycosphingolipid metabolism, but it remains to be established. It appears to have drifted more slowly than confirmed pseudogenes in the glycosyltransferase 6 family, suggesting that it has remained under evolutionary pressure.

Biological Process

Carbohydrate metabolic process Source: InterPro
Glycolipid biosynthetic process Source: ProtInc
Lipid glycosylation Source: GO_Central
Protein glycosylation Source: UniProtKB-UniPathway

Cellular Location

Golgi apparatus membrane

Topology

Cytoplasmic: 1-5
Helical: 6-26
Lumenal: 27-347

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Rat Anti-GBGT1 Recombinant Antibody (33B12) (CAT#: CBMAB-G2407-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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