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Rabbit Anti-GBP3 Recombinant Antibody (EG1296) (CBMAB-EN1567-LY)

The product is antibody recognizes GBP3. The antibody EG1296 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:10000.
See all GBP3 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1296
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GBP3.
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Guanylate Binding Protein 3
Introduction
This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2017]
Entrez Gene ID
UniProt ID
Alternative Names
Guanylate Binding Protein 3; Guanine Nucleotide-Binding Protein 3; GTP-Binding Protein 3; EC 3.6.5.-; GBP-3;
Function
Exhibits antiviral activity against influenza virus.
Biological Process
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: UniProtKB
Cellular response to tumor necrosis factor Source: UniProtKB
Defense response to virus Source: UniProtKB-KW
Cellular Location
Cytoplasm; Golgi apparatus membrane; Perinuclear region. Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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