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Rabbit Anti-GCFC2 Recombinant Antibody (EG1298) (CBMAB-EN1569-LY)

The product is antibody recognizes GCF. The antibody EG1298 immunoassay techniques such as: WB: 1:500~1:1000 ELISA: 1:20000.
See all GCFC2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1298
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:20000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GCF.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GC-rich sequence DNA-binding factor 2
Introduction
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Entrez Gene ID
6936
UniProt ID
P16383
Alternative Names
GCF; TCF9; DNABF; C2orf3
Function
Involved in pre-mRNA splicing through regulating spliceosome C complex formation (PubMed:24304693).

May play a role during late-stage splicing events and turnover of excised introns (PubMed:24304693).
Biological Process
mRNA splicing, via spliceosome Source: GO_Central
Negative regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Spliceosomal complex assembly Source: UniProtKB
Cellular Location
Nucleoplasm; Nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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