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Mouse Anti-GDE1 Recombinant Antibody (2H6) (CBMAB-G2691-LY)

This product is antibody recognizes GDE1. The antibody 2H6 immunoassay techniques such as: ELISA, ICC, IF.
See all GDE1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2H6
Antibody Isotype
IgG2a, κ
Application
ELISA, ICC, IF

Basic Information

Immunogen
GDE1 (NP_057725, 31 a.a. ~ 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2-1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1
Entrez Gene ID
51573
UniProt ID
Q9NZC3
Alternative Names
363E6.2; MIR16
Function
Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol (By similarity).

Hydrolyzes glycerophospho-N-acylethanolamines to N-acylethanolamines in the brain and partipates to bioactive N-acylethanolamines biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N-oleoylethanolamine (an anorexic). In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl-lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity (By similarity).

Has little or no activity towards glycerophosphocholine (By similarity).
Biological Process
Ethanolamine metabolic process Source: UniProtKB
Glycerophospholipid catabolic process Source: Reactome
Lipid metabolic process Source: UniProtKB
N-acylethanolamine metabolic process Source: UniProtKB
Phospholipid metabolic process Source: UniProtKB
Cellular Location
Cell membrane; Cytoplasmic vesicle membrane. Perinuclear vesicles and cell membrane.
Topology
Cytoplasmic: 1-3
Helical: 4-24
Lumenal: 25-247
Helical: 248-268
Cytoplasmic: 269-331
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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