Mouse Anti-GDPD2 Recombinant Antibody (501016) (CBMAB-G0323-LY)

Name: Mouse Anti-GDPD2 Recombinant Antibody (501016)
SKU: CBMAB-G0323-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

501016

Application

ICC

Immunogen

HEK293 human embryonic kidney cell line transfected with human GDPD2, Accession # Q9HCC8

Specificity

Human, Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

lyophilized

Buffer

Trehalose

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

glycerophosphodiester phosphodiesterase domain containing 2

Introduction

This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Entrez Gene ID

Human	54857
Mouse	71584

UniProt ID

Human	Q9HCC8
Mouse	Q9ESM6

Alternative Names

Glycerophosphodiester Phosphodiesterase Domain Containing 2; Osteoblast Differentiation Promoting Factor; Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 2; Glycerophosphodiester Phosphodiesterase 3; OBDPF; GDE3; Glycerophosphoinositol Inositolphosphodiesterase GDPD2; EC 3.1.4.43;

Function

Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity).

Biological Process

Actin filament reorganization Source: Ensembl
Lipid metabolic process Source: InterPro
Positive regulation of osteoblast differentiation Source: Ensembl

Cellular Location

Cytoskeleton; Cytoplasm; Cell membrane. Colocalizes with the actin cytoskeleton.

Topology

Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-85
Helical: 86-106
Cytoplasmic: 107-121
Helical: 122-142
Extracellular: 143-154
Helical: 155-175
Cytoplasmic: 176-188
Helical: 189-209
Extracellular: 210-490
Helical: 491-511
Cytoplasmic: 512-539

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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