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Mouse Anti-GDPD2 Recombinant Antibody (501016) (CBMAB-G0323-LY)

This product is antibody recognizes GDPD2. The antibody 501016 immunoassay techniques such as: ICC.
See all GDPD2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
501016
Antibody Isotype
IgG2a
Application
ICC

Basic Information

Immunogen
HEK293 human embryonic kidney cell line transfected with human GDPD2, Accession # Q9HCC8
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
lyophilized
Buffer
Trehalose
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
glycerophosphodiester phosphodiesterase domain containing 2
Introduction
This gene encodes a member of the glycerophosphodiester phosphodiesterase enzyme family. The encoded protein hydrolyzes glycerophosphoinositol to produce inositol 1-phosphate and glycerol. This protein may have a role in osteoblast differentiation and growth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Entrez Gene ID
Human54857
Mouse71584
UniProt ID
HumanQ9HCC8
MouseQ9ESM6
Alternative Names
Glycerophosphodiester Phosphodiesterase Domain Containing 2; Osteoblast Differentiation Promoting Factor; Glycerophosphodiester Phosphodiesterase Domain-Containing Protein 2; Glycerophosphodiester Phosphodiesterase 3; OBDPF; GDE3; Glycerophosphoinositol Inositolphosphodiesterase GDPD2; EC 3.1.4.43;
Function
Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity).
Biological Process
Actin filament reorganization Source: Ensembl
Lipid metabolic process Source: InterPro
Positive regulation of osteoblast differentiation Source: Ensembl
Cellular Location
Cytoskeleton; Cytoplasm; Cell membrane. Colocalizes with the actin cytoskeleton.
Topology
Cytoplasmic: 1-38
Helical: 39-59
Extracellular: 60-85
Helical: 86-106
Cytoplasmic: 107-121
Helical: 122-142
Extracellular: 143-154
Helical: 155-175
Cytoplasmic: 176-188
Helical: 189-209
Extracellular: 210-490
Helical: 491-511
Cytoplasmic: 512-539
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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