Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-GFRA1 Recombinant Antibody (3H8) (CBMAB-1566-CN)


See all GFRA1 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
3H8
Antibody Isotype
IgG2b
Application
FC, IP

Basic Information

Immunogen
Recombinant human GFRα1 extracellular domain (aa. 24-440)
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GDNF family receptor alpha 1
Introduction
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. The protein mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
Entrez Gene ID
2674
UniProt ID
P56159
Alternative Names
GDNFR; RET1L; RETL1; TRNR1; GDNFRA; GFR-ALPHA-1
Function
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).
Biological Process
Cell surface receptor signaling pathway Source: UniProtKB
Nervous system development Source: GO_Central
Cellular Location
Cell membrane; Endosome; Multivesicular body; Trans-Golgi network. Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and multivesicular bodies.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-GFRA1 Recombinant Antibody (3H8)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry