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Rabbit Anti-GGCT Recombinant Antibody (CBLG1-2746) (CBMAB-G3249-LY)

This product is antibody recognizes GGCT. The antibody CBLG1-2746 immunoassay techniques such as: WB.
See all GGCT antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBLG1-2746
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Gamma-Glutamylcyclotransferase
Introduction
The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Entrez Gene ID
79017
UniProt ID
O75223
Alternative Names
Gamma-Glutamylcyclotransferase; Cytochrome C-Releasing Factor 21; C7orf24; CRF21; Chromosome 7 Open Reading Frame 24; Gamma -Glutamyl Cyclotransferase; EC 4.3.2.9; GCTG; GGC;
Function
Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.
Biological Process
Release of cytochrome c from mitochondria Source: UniProtKB
Cellular Location
Cytosol; Extracellular exosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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