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Rabbit Anti-GHITM Recombinant Antibody (EG1309) (CBMAB-EN1585-LY)


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Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG1309
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human GHITM.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
growth hormone inducible transmembrane protein
Entrez Gene ID
27069
UniProt ID
Q9H3K2
Alternative Names
DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282
Function
Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Biological Process
Apoptotic process Source: UniProtKB-KW
Inner mitochondrial membrane organization Source: FlyBase
Negative regulation of release of cytochrome c from mitochondria Source: FlyBase
Positive regulation of mitochondrial ATP synthesis coupled electron transport Source: FlyBase
Cellular Location
Mitochondrion inner membrane
Topology
Mitochondrial matrix: 46-82
Helical: 83-103
Mitochondrial intermembrane: 104-125
Helical: 126-146
Mitochondrial matrix: 147-159
Helical: 160-180
Mitochondrial intermembrane: 181-190
Helical: 191-211
Mitochondrial matrix: 212-213
Helical: 214-234
Mitochondrial intermembrane: 235-244
Helical: 245-265
Mitochondrial matrix: 266-271
Helical: 272-292
Mitochondrial intermembrane: 293-345
More Infomation
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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