GHITM

The pattern of Ghitm expression suggested that once Ghitm mRNA was expressed in the putative brain region of mouse embryo, Ghitm-expressing cells spread ubiquitously throughout all tissues during embryonic development.

Full Name

growth hormone inducible transmembrane protein

Function

Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.

Biological Process

Apoptotic process Source: UniProtKB-KW
Inner mitochondrial membrane organization Source: FlyBase
Negative regulation of release of cytochrome c from mitochondria Source: FlyBase
Positive regulation of mitochondrial ATP synthesis coupled electron transport Source: FlyBase

Cellular Location

Mitochondrion inner membrane

Topology

Mitochondrial matrix: 46-82
Helical: 83-103
Mitochondrial intermembrane: 104-125
Helical: 126-146
Mitochondrial matrix: 147-159
Helical: 160-180
Mitochondrial intermembrane: 181-190
Helical: 191-211
Mitochondrial matrix: 212-213
Helical: 214-234
Mitochondrial intermembrane: 235-244
Helical: 245-265
Mitochondrial matrix: 266-271
Helical: 272-292
Mitochondrial intermembrane: 293-345

Anti-GHITM antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Rabbit Anti-GHITM Recombinant Antibody (EG1309) (CBMAB-EN1585-LY)

Datasheet

SDS

Target: GHITM

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: EG1309

Application*: WB: 1:500~1:1000 ELISA: 1:10000

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)