GHITM
The pattern of Ghitm expression suggested that once Ghitm mRNA was expressed in the putative brain region of mouse embryo, Ghitm-expressing cells spread ubiquitously throughout all tissues during embryonic development.
Full Name
growth hormone inducible transmembrane protein
Function
Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.
Biological Process
Apoptotic process Source: UniProtKB-KW
Inner mitochondrial membrane organization Source: FlyBase
Negative regulation of release of cytochrome c from mitochondria Source: FlyBase
Positive regulation of mitochondrial ATP synthesis coupled electron transport Source: FlyBase
Inner mitochondrial membrane organization Source: FlyBase
Negative regulation of release of cytochrome c from mitochondria Source: FlyBase
Positive regulation of mitochondrial ATP synthesis coupled electron transport Source: FlyBase
Cellular Location
Mitochondrion inner membrane
Topology
Mitochondrial matrix: 46-82
Helical: 83-103
Mitochondrial intermembrane: 104-125
Helical: 126-146
Mitochondrial matrix: 147-159
Helical: 160-180
Mitochondrial intermembrane: 181-190
Helical: 191-211
Mitochondrial matrix: 212-213
Helical: 214-234
Mitochondrial intermembrane: 235-244
Helical: 245-265
Mitochondrial matrix: 266-271
Helical: 272-292
Mitochondrial intermembrane: 293-345
Helical: 83-103
Mitochondrial intermembrane: 104-125
Helical: 126-146
Mitochondrial matrix: 147-159
Helical: 160-180
Mitochondrial intermembrane: 181-190
Helical: 191-211
Mitochondrial matrix: 212-213
Helical: 214-234
Mitochondrial intermembrane: 235-244
Helical: 245-265
Mitochondrial matrix: 266-271
Helical: 272-292
Mitochondrial intermembrane: 293-345
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Anti-GHITM antibodies
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Target: GHITM
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1309
Application*: WB: 1:500~1:1000 ELISA: 1:10000
Target: GHITM
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: EG1309
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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