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Rabbit Anti-GHRH Recombinant Antibody (CBLG1-1121) (CBMAB-G3393-LY)

This product is antibody recognizes GHRH. The antibody CBLG1-1121 immunoassay techniques such as: WB.
See all GHRH antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBLG1-1121
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Peptide, please contact us for details
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Growth Hormone Releasing Hormone
Introduction
This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Entrez Gene ID
2691
UniProt ID
P01286
Alternative Names
GHRF; GRF; INN
Function
GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.
Biological Process
Adenohypophysis development Source: BHF-UCL
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: BHF-UCL
Cell-cell signaling Source: ProtInc
Growth hormone secretion Source: MGI
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of circadian sleep/wake cycle, REM sleep Source: BHF-UCL
Positive regulation of growth hormone secretion Source: BHF-UCL
Positive regulation of insulin-like growth factor receptor signaling pathway Source: BHF-UCL
Positive regulation of multicellular organism growth Source: BHF-UCL
Response to food Source: BHF-UCL
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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