Mouse Anti-GHRH Recombinant Antibody (CBLG1-1122) (CBMAB-G3395-LY)

Name: Mouse Anti-GHRH Recombinant Antibody (CBLG1-1122)
SKU: CBMAB-G3395-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBLG1-1122

Application

Immunogen

Growth Hormone Releasing Hormone

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

50% glycerol

Preservative

0.02% NaN3

Concentration

0.5 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Growth Hormone Releasing Hormone

Introduction

This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Entrez Gene ID

2691

UniProt ID

P01286

Alternative Names

Growth Hormone Releasing Hormone; Somatocrinin; Sermorelin; Somatoliberin; Somatorelin; GHRF;

Function

GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.

Biological Process

Adenohypophysis development Source: BHF-UCL
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: BHF-UCL
Cell-cell signaling Source: ProtInc
Growth hormone secretion Source: MGI
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of circadian sleep/wake cycle, REM sleep Source: BHF-UCL
Positive regulation of growth hormone secretion Source: BHF-UCL
Positive regulation of insulin-like growth factor receptor signaling pathway Source: BHF-UCL
Positive regulation of multicellular organism growth Source: BHF-UCL
Response to food Source: BHF-UCL

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Rabbit Anti-GHRH Recombinant Antibody (CBLG1-1121) (CAT#: CBMAB-G3393-LY)

Mouse Anti-GHRH Recombinant Antibody (C7) (CAT#: CBMAB-AP2527LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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