Mouse Anti-GHSR Recombinant Antibody (CBFYH-0355) (V2LY-1225-LY1291)

growth hormone secretagogue receptor

Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

Actin polymerization or depolymerization Source: UniProtKB
Adult feeding behavior Source: HGNC-UCL
Cellular response to insulin-like growth factor stimulus Source: Ensembl
Cellular response to insulin stimulus Source: Ensembl
Cellular response to lipopolysaccharide Source: Ensembl
Cellular response to thyroid hormone stimulus Source: Ensembl
Decidualization Source: UniProtKB
Ghrelin secretion Source: Ensembl
G protein-coupled receptor signaling pathway Source: HGNC-UCL
Growth hormone secretion Source: HGNC-UCL
Hormone-mediated signaling pathway Source: HGNC-UCL
Learning or memory Source: Ensembl
Negative regulation of appetite Source: Ensembl
Negative regulation of inflammatory response Source: UniProtKB
Negative regulation of insulin secretion Source: Ensembl
Negative regulation of interleukin-1 beta production Source: UniProtKB
Negative regulation of interleukin-6 production Source: UniProtKB
Negative regulation of locomotion involved in locomotory behavior Source: Ensembl
Negative regulation of macrophage apoptotic process Source: Ensembl
Negative regulation of norepinephrine secretion Source: Ensembl
Negative regulation of tumor necrosis factor production Source: UniProtKB
Positive regulation of appetite Source: HGNC-UCL
Positive regulation of eating behavior Source: Ensembl
Positive regulation of fatty acid metabolic process Source: Ensembl
Positive regulation of insulin-like growth factor receptor signaling pathway Source: Ensembl
Positive regulation of multicellular organism growth Source: HGNC-UCL
Positive regulation of small intestinal transit Source: Ensembl
Positive regulation of small intestine smooth muscle contraction Source: Ensembl
Positive regulation of sprouting angiogenesis Source: Ensembl
Positive regulation of vascular endothelial cell proliferation Source: Ensembl
Postsynaptic modulation of chemical synaptic transmission Source: Ensembl
Regulation of gastric motility Source: Ensembl
Regulation of growth hormone secretion Source: Ensembl
Regulation of hindgut contraction Source: Ensembl
Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane Source: Ensembl
Regulation of postsynapse organization Source: Ensembl
Regulation of synapse assembly Source: Ensembl
Regulation of transmission of nerve impulse Source: Ensembl
Response to dexamethasone Source: Ensembl
Response to estradiol Source: Ensembl
Response to follicle-stimulating hormone Source: Ensembl
Response to food Source: Ensembl
Response to growth hormone Source: Ensembl
Response to hormone Source: UniProtKB
Response to monosodium glutamate Source: Ensembl
Spermatogenesis Source: Ensembl

Cell membrane

Growth hormone deficiency, isolated partial (GHDP):
A disorder characterized by partial growth hormone deficiency resulting in growth delay and short stature, sometimes associated with recurrent episodes of abdominal pain, vomiting, ketosis and hypoglycemia.

Extracellular: 1-40
Helical: 41-66
Cytoplasmic: 67-72
Helical: 73-96
Extracellular: 97-117
Helical: 118-139
Cytoplasmic: 140-162
Helical: 163-183
Extracellular: 184-211
Helical: 212-235
Cytoplasmic: 236-263
Helical: 264-285
Extracellular: 286-302
Helical: 303-326
Cytoplasmic: 327-366