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Rabbit Anti-GIF Recombinant Antibody (CBLG1-1158) (CBMAB-G3479-LY)

This product is antibody recognizes GIF. The antibody CBLG1-1158 immunoassay techniques such as: WB.
See all GIF antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBLG1-1158
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Recombinant Human Gastric intrinsic factor / GIF Protein
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
gastric intrinsic factor (vitamin B synthesis)
Introduction
This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008]
Entrez Gene ID
2694
UniProt ID
P27352
Alternative Names
Gastric Intrinsic Factor; Gastric Intrinsic Factor (Vitamin B Synthesis); Intrinsic Factor; IFMH; INF; IF; TCN3;
Function
Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.
Biological Process
Cobalamin transport Source: UniProtKB
Cobalt ion transport Source: UniProtKB-KW
Cellular Location
Secreted
Involvement in disease
Hereditary intrinsic factor deficiency (IFD):
Autosomal recessive disorder characterized by megaloblastic anemia.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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