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Mouse Anti-GINS2 Recombinant Antibody (3H4) (CBMAB-G3502-LY)

This product is antibody recognizes GINS2. The antibody 3H4 immunoassay techniques such as: ELISA, WB.
See all GINS2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3H4
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
GINS2 (AAH03186, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2-1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GINS complex subunit 2 (Psf2 homolog)
Introduction
The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Entrez Gene ID
51659
UniProt ID
Q9Y248
Alternative Names
GINS Complex Subunit 2; GINS Complex Subunit 2 (Psf2 Homolog); PSF2; DNA Replication Complex GINS Protein PSF2; HSPC037; Pfs2;
Function
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.
Biological Process
DNA replication Source: UniProtKB-KW
Double-strand break repair via break-induced replication Source: GO_Central
Cellular Location
Nucleus; Chromosome. Associates with chromatin.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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