GINS2

The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1 (GINS1; MIM 610608), Psf2, and Psf3 (GINS3; MIM 610610). The formation of this complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM

Full Name

GINS complex subunit 2 (Psf2 homolog)

Function

The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

Biological Process

DNA replication Source: UniProtKB-KW
Double-strand break repair via break-induced replication Source: GO_Central

Cellular Location

Nucleus; Chromosome. Associates with chromatin.

Anti-GINS2 antibodies

Mouse Anti-GINS2 Recombinant Antibody (F-7) (CBMAB-P0357-YC)

Datasheet

SDS

Target: GINS2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: F-7

Application*: WB, IP, IF, E

Mouse Anti-GINS2 Recombinant Antibody (3H4) (CBMAB-G3502-LY)

Datasheet

SDS

Target: GINS2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 3H4

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)