Mouse Anti-GIT2 Recombinant Antibody (CBLG1-1182) (CBMAB-G3535-LY)

Name: Mouse Anti-GIT2 Recombinant Antibody (CBLG1-1182)
SKU: CBMAB-G3535-LY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBLG1-1182

Application

ELISA, IF, IHC-P, WB

Specificity

Human

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

0.5 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

GIT ArfGAP 2

Introduction

This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]

Entrez Gene ID

9815

UniProt ID

Q14161

Alternative Names

GIT ArfGAP 2; G Protein-Coupled Receptor Kinase Interacting ArfGAP 2; Cool-Interacting Tyrosine-Phosphorylated Protein 2; G Protein-Coupled Receptor Kinase-Interactor 2; GRK-Interacting Protein 2; Paxillin Kinase Linker; ARF GAP GIT2; CAT-2;

Function

GTPase-activating protein for ADP ribosylation factor family members, including ARF1.

Biological Process

Regulation of G protein-coupled receptor signaling pathway Source: ProtInc

Cellular Location

Nucleoplasm; Focal adhesion

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-GIT2 Recombinant Antibody (CBLG1-1182) (CAT#: V2LY-1225-LY1347)

Antibody Pairs

GIT2 Matched Antibody Pair (483) (CAT#: APMAB-483LY)

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Mouse Anti-GIT2 Recombinant Antibody (CBLG1-1184) (CAT#: V2LY-1225-LY1348)

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Rabbit Anti-GIT2 Recombinant Antibody (D11B8) (CAT#: CBMAB-G3529-LY)

GIT2 Matched Antibody Pair (483) (CAT#: APMAB-483LY)

Mouse Anti-GIT2 Recombinant Antibody (CBLG1-1182) (CAT#: V2LY-1225-LY1347)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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