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Mouse Anti-GLIS1 Recombinant Antibody (CBLG1-3180) (CBMAB-G3797-LY)

This product is antibody recognizes GLIS1. The antibody CBLG1-3180 immunoassay techniques such as: WB.
See all GLIS1 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat
Clone
CBLG1-3180
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glis Family Zinc Finger 1
Introduction
GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
Entrez Gene ID
Mouse230587
Rat298732
UniProt ID
MouseQ8K1M4
RatF1LVY3
Function
Acts as both a repressor and activator of transcription (PubMed:21654807).

Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).

By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807).

Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (By similarity).
Biological Process
Cell differentiation Source: UniProtKB-KW
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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