GLIS1

GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
Full Name
Glis Family Zinc Finger 1
Function
Acts as both a repressor and activator of transcription (PubMed:21654807).

Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).

By controlling the expression of genes involved in cell differentiation inhibits the lineage commitment of multipotent cells (PubMed:21654807).

Prevents, for instance, the differentiation of multipotent mesenchymal cells into adipocyte and osteoblast (By similarity).
Biological Process
Cell differentiation Source: UniProtKB-KW
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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Anti-GLIS1 antibodies

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Mouse Anti-GLIS1 Recombinant Antibody (CBLG1-3182) (CBMAB-G3799-LY)

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Target: GLIS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3182
Application*: WB
Datasheet SDS

Mouse Anti-GLIS1 Recombinant Antibody (CBLG1-3180) (CBMAB-G3797-LY)

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Target: GLIS1
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat
Clone: CBLG1-3180
Application*: WB
Datasheet SDS

Mouse Anti-GLIS1 Recombinant Antibody (CBLG1-3182) (V2LY-1225-LY1479)

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Target: GLIS1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBLG1-3182
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-GLIS1 Recombinant Antibody (CBLG1-3180) (V2LY-1225-LY1478)

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Target: GLIS1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: CBLG1-3180
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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