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Mouse Anti-GPAT4 Recombinant Antibody (4C12) (CBMAB-A4434-YC)

Provided herein is a Mouse monoclonal antibody against Human Glycerol-3-Phosphate Acyltransferase 4. The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all GPAT4 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4C12
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
AGPAT6 (NP_848934. 1, 39-137 aa) partial recombinant protein with GST tag. Immunogen sequence: SFGIRKLYMK SLLKIFAWAT LRMERGAKEK NHQLYKPYTN GIIAKDPTSL EEEIKEIRRS GSSKALDNTP EFELSDIFYF CRKGMETIMD DEVTKRFSA
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 39-137

Target

Full Name
Glycerol-3-Phosphate Acyltransferase 4
Introduction
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.
Entrez Gene ID
137964
UniProt ID
Q86UL3
Alternative Names
Glycerol-3-Phosphate Acyltransferase 4; 1-Acylglycerol-3-Phosphate O-Acyltransferase 6 (Lysophosphatidic Acid Acyltransferase, Zeta); 1-Acylglycerol-3-Phosphate O-Acyltransferase 6; Lysophosphatidic Acid Acyltransferase Zeta; 1-AGP Acyltransferase 6; EC 2
Function
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:18238778).

Active against both saturated and unsaturated long-chain fatty acyl-CoAs (PubMed:18238778).
Biological Process
Acyl-CoA metabolic process Source: UniProtKB
CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Diacylglycerol metabolic process Source: Ensembl
Fatty acid metabolic process Source: Ensembl
Glandular epithelial cell maturation Source: Ensembl
Lactation Source: UniProtKB
Lipid biosynthetic process Source: UniProtKB
Phosphatidic acid biosynthetic process Source: Reactome
Phosphatidylcholine biosynthetic process Source: UniProtKB
Regulation of multicellular organism growth Source: Ensembl
Triglyceride biosynthetic process Source: UniProtKB
Cellular Location
Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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