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GPAT4

Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.
Full Name
Glycerol-3-Phosphate Acyltransferase 4
Function
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:18238778).

Active against both saturated and unsaturated long-chain fatty acyl-CoAs (PubMed:18238778).
Biological Process
Acyl-CoA metabolic process Source: UniProtKB
CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Diacylglycerol metabolic process Source: Ensembl
Fatty acid metabolic process Source: Ensembl
Glandular epithelial cell maturation Source: Ensembl
Lactation Source: UniProtKB
Lipid biosynthetic process Source: UniProtKB
Phosphatidic acid biosynthetic process Source: Reactome
Phosphatidylcholine biosynthetic process Source: UniProtKB
Regulation of multicellular organism growth Source: Ensembl
Triglyceride biosynthetic process Source: UniProtKB
Cellular Location
Endoplasmic reticulum membrane

Anti-GPAT4 antibodies

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Target: GPAT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C12
Application*: WB, E
Target: GPAT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C12
Application*: E, IF, WB
Target: GPAT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYC-A966
Application*: E, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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