GPAT4
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.
Full Name
Glycerol-3-Phosphate Acyltransferase 4
Function
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:18238778).
Active against both saturated and unsaturated long-chain fatty acyl-CoAs (PubMed:18238778).
Active against both saturated and unsaturated long-chain fatty acyl-CoAs (PubMed:18238778).
Biological Process
Acyl-CoA metabolic process Source: UniProtKB
CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Diacylglycerol metabolic process Source: Ensembl
Fatty acid metabolic process Source: Ensembl
Glandular epithelial cell maturation Source: Ensembl
Lactation Source: UniProtKB
Lipid biosynthetic process Source: UniProtKB
Phosphatidic acid biosynthetic process Source: Reactome
Phosphatidylcholine biosynthetic process Source: UniProtKB
Regulation of multicellular organism growth Source: Ensembl
Triglyceride biosynthetic process Source: UniProtKB
CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Diacylglycerol metabolic process Source: Ensembl
Fatty acid metabolic process Source: Ensembl
Glandular epithelial cell maturation Source: Ensembl
Lactation Source: UniProtKB
Lipid biosynthetic process Source: UniProtKB
Phosphatidic acid biosynthetic process Source: Reactome
Phosphatidylcholine biosynthetic process Source: UniProtKB
Regulation of multicellular organism growth Source: Ensembl
Triglyceride biosynthetic process Source: UniProtKB
Cellular Location
Endoplasmic reticulum membrane
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Anti-GPAT4 antibodies
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Target: GPAT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYC-A966
Application*: E, WB
Target: GPAT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C12
Application*: WB, E
Target: GPAT4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 4C12
Application*: E, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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