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Mouse Anti-GPHA2 Recombinant Antibody (CBLG1-1608) (CBMAB-G4544-LY)

This product is antibody recognizes GPHA2. The antibody CBLG1-1608 immunoassay techniques such as: ELISA.
See all GPHA2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-1608
Antibody Isotype
IgG1
Application
ELISA

Basic Information

Immunogen
Recombinant Human GPHA2 / glycoprotein hormone alpha 2 Protein
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glycoprotein Hormone Alpha 2
Introduction
GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008]
Entrez Gene ID
170589
UniProt ID
Q96T91
Alternative Names
Glycoprotein Hormone Alpha 2; Putative Secreted Protein Zsig51; Thyrostimulin Subunit Alpha; Cysteine Knot Protein; Glycoprotein Alpha 2; ZSIG51; GPA2; Glycoprotein Hormone Alpha-2; A2;
Function
Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production (PubMed:12045258).

Plays a central role in controlling thyroid cell metabolism (PubMed:12045258).
Biological Process
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: UniProtKB
Cell surface receptor signaling pathway Source: UniProtKB
Cellular Location
Secreted
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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