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Mouse Anti-GPR19 Recombinant Antibody (K152D10) (CBMAB-G4647-LY)

This product is antibody recognizes GPR19. The antibody K152D10 immunoassay techniques such as: FC.
See all GPR19 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
K152D10
Antibody Isotype
IgG1, κ
Application
FC

Basic Information

Immunogen
N-terminal Peptide
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.09% sodium azide
Concentration
0.5 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
G protein-coupled receptor 19
Entrez Gene ID
2842
UniProt ID
Q15760
Function
Orphan receptor.
Biological Process
G protein-coupled receptor signaling pathway Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 1-69
Helical: 70-90
Cytoplasmic: 91-102
Helical: 103-123
Extracellular: 124-143
Helical: 144-161
Cytoplasmic: 162-182
Helical: 183-203
Extracellular: 204-221
Helical: 222-242
Cytoplasmic: 243-277
Helical: 278-298
Extracellular: 299-309
Helical: 310-325
Cytoplasmic: 326-415

Mushala, B. A., Xie, B., Sipula, I. J., Stoner, M. W., Thapa, D., Manning, J. R., ... & Scott, I. (2023). G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction. Scientific Reports, 13(1), 6134.

Maudsley, S., Schrauwen, C., Harputluoğlu, İ., Walter, D., Leysen, H., & McDonald, P. (2023). GPR19 Coordinates Multiple Molecular Aspects of Stress Responses Associated with the Aging Process. International Journal of Molecular Sciences, 24(10), 8499.

Maudsley, S., Walter, D., Schrauwen, C., Van Loon, N., Harputluoğlu, İ., Lenaerts, J., & McDonald, P. (2022). Intersection of the Orphan G Protein-Coupled Receptor, GPR19, with the Aging Process. International journal of molecular sciences, 23(21), 13598.

Walter, D., Leysen, H., Christiaenssen, B., & Maudsley, S. (2022). The TM2. 50 Aspartate of the TM1‐2‐7 Hydrogen‐Bond Network Modulates Signaling Bias Effects in G Protein‐Coupled Receptor 19 (GPR19). The FASEB Journal, 36.

Yamaguchi, Y., Murai, I., Goto, K., Doi, S., Zhou, H., Setsu, G., ... & Doi, M. (2021). Gpr19 is a circadian clock-controlled orphan GPCR with a role in modulating free-running period and light resetting capacity of the circadian clock. Scientific Reports, 11(1), 22406.

Klatt, W., Wallner, S., Brochhausen, C., Stolwijk, J. A., & Schreml, S. (2020). Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors. Scientific Reports, 10(1), 1-12.

Nassios, A., Wallner, S., Haferkamp, S., Klingelhöffer, C., Brochhausen, C., & Schreml, S. (2019). Expression of proton‐sensing G‐protein‐coupled receptors in selected skin tumors. Experimental Dermatology, 28(1), 66-71.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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