Human GPR19 ELISA Kit (V2LY-0626-LY5573)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.017 ng/mL
Detection Range
0.05-20 ng/mL
Sample Type
Serum, Plasma, Urine, Ascites, Cerebrospinal fluid, Tissue
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
47.7 kDa
Components
  • Standard Solution: 0.5ml x1
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard Diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop Solution: 6ml x1
  • Substrate Solution A: 6ml x1
  • Substrate Solution B: 6ml x1
  • Wash Buffer Concentrate (25x): 20ml x1
  • Biotinylated Antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
G protein-coupled receptor 19
Function
Orphan receptor.
Biological Process
G protein-coupled receptor signaling pathway Source: ProtInc
Cellular Location
Cell membrane
Topology
Extracellular: 1-69
Helical: 70-90
Cytoplasmic: 91-102
Helical: 103-123
Extracellular: 124-143
Helical: 144-161
Cytoplasmic: 162-182
Helical: 183-203
Extracellular: 204-221
Helical: 222-242
Cytoplasmic: 243-277
Helical: 278-298
Extracellular: 299-309
Helical: 310-325
Cytoplasmic: 326-415

Mushala, B. A., Xie, B., Sipula, I. J., Stoner, M. W., Thapa, D., Manning, J. R., ... & Scott, I. (2023). G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction. Scientific Reports, 13(1), 6134.

Maudsley, S., Schrauwen, C., Harputluoğlu, İ., Walter, D., Leysen, H., & McDonald, P. (2023). GPR19 Coordinates Multiple Molecular Aspects of Stress Responses Associated with the Aging Process. International Journal of Molecular Sciences, 24(10), 8499.

Maudsley, S., Walter, D., Schrauwen, C., Van Loon, N., Harputluoğlu, İ., Lenaerts, J., & McDonald, P. (2022). Intersection of the Orphan G Protein-Coupled Receptor, GPR19, with the Aging Process. International journal of molecular sciences, 23(21), 13598.

Walter, D., Leysen, H., Christiaenssen, B., & Maudsley, S. (2022). The TM2. 50 Aspartate of the TM1‐2‐7 Hydrogen‐Bond Network Modulates Signaling Bias Effects in G Protein‐Coupled Receptor 19 (GPR19). The FASEB Journal, 36.

Yamaguchi, Y., Murai, I., Goto, K., Doi, S., Zhou, H., Setsu, G., ... & Doi, M. (2021). Gpr19 is a circadian clock-controlled orphan GPCR with a role in modulating free-running period and light resetting capacity of the circadian clock. Scientific Reports, 11(1), 22406.

Klatt, W., Wallner, S., Brochhausen, C., Stolwijk, J. A., & Schreml, S. (2020). Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors. Scientific Reports, 10(1), 1-12.

Nassios, A., Wallner, S., Haferkamp, S., Klingelhöffer, C., Brochhausen, C., & Schreml, S. (2019). Expression of proton‐sensing G‐protein‐coupled receptors in selected skin tumors. Experimental Dermatology, 28(1), 66-71.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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