Mouse Anti-GRAP2 Monoclonal Antibody (CBFYH-2984) (CBMAB-H1341-FY)

Name: Mouse Anti-GRAP2 Monoclonal Antibody (CBFYH-2984)
SKU: CBMAB-H1341-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-2984

Application

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

4.8 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

GRB2-Related Adaptor Protein 2

Introduction

This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Entrez Gene ID

9402

UniProt ID

O75791

Alternative Names

GRB2-Related Adaptor Protein 2; Hematopoietic Cell-Associated Adapter Protein GrpL; Growth Factor Receptor-Binding Protein; SH3-SH2-SH3 Adapter Mona; Grf40 Adapter Protein; Adapter Protein GRID; GRB-2-Like Protein; Grf-40; GRB2L; GRBLG; GrbX; GADS; GRID

Function

Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.

Biological Process

Cell-cell signaling Source: ProtInc
Ras protein signal transduction Source: ProtInc

Cellular Location

Endosome; Nucleus; Cytoplasm

Lin, S., Zhu, J., Mao, X., Lin, G., Yang, D., Guan, Y., & Gao, J. (2023). GRAP2: A Novel Immune-Related Prognosis Biomarker in Cervical Cancer. Clinical and Experimental Obstetrics & Gynecology, 50(3), 57.

Song, S., Deng, X., Jiang, S., Tian, C., Han, J., Chai, J., ... & Luo, Z. (2022). GRAP2 is a prognostic biomarker and correlated with immune infiltration in lung adenocarcinoma. Journal of Clinical Laboratory Analysis, 36(11), e24662.

Fujita, H., Aratani, S., & Nakajima, T. (2021). Grap2 cyclin D interacting protein negatively regulates CREB‑binding protein, inhibiting fibroblast‑like synoviocyte growth. Molecular Medicine Reports, 23(4), 1-1.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

GRAP2 Matched Antibody Pair (497) (CAT#: APMAB-497LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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